carcinogen相关论文
Hepatic CYPs involved in both the detoxification and metabolic activation of many carcinogens.In order to reveal the rol......
AIM:To investigate the expression of 1A6 gene in the lesionsduring the development of intestinal gastric carcinoma.METH......
Loss of myeloid-related proteins 8 and myeloid-related proteins 14 expression in human esophageal sq
AIM:To study the expression of myeloid-related proteins(MRP)8 and myeloid-related proteins(MRP)14 in humanesophageal sq......
AIM: To investigate the relationship between Helicobacter pylori (H pylori) infection, microsatellite instability and th......
机体的葡萄糖在体内代谢途径包括糖酵解和氧化磷酸化。而肿瘤细胞代谢依赖于糖酵解,增强了肿瘤细胞对体内微环境的适应性,促进了肿瘤......
AIM:To investigate the expression of COX-2 proteins ingastric mucosal lesions and to assess the relationshipbetween COX......
Objective: To study the relationship between one polymorphism in the promoter of the DNA repair gene XPA and the suscept......
Recently,Ng et al.reported that the A:T > T:A substitutions,proposed to be a signature of aristolochic acid (AA) exposure......
测定了不同牌号卷烟烟气焦油量与烟气中的3,4-苯并[a]芘、N-亚硝胺等致癌物含量.结果发现,市售不同牌号卷烟烟气焦油量与致癌物含......
黄曲霉毒素及其他真菌毒素的降解技术一直是全球食品安全领域的研究热点。新型降解方式也在不断的探索中,主要有辐照、臭氧、电解......
BACKGROUND:Gallbladder cancer(GBC)is a rare disease but a leading cause of cancer-related death worldwide.A number of et......
本文应用人胚肺成纤维细胞转化试验,对氯化镉的致癌性进行研究。结果表明:氯化镉在浓度0.004~0.04μM/ml范围之内,可使人胚肺细胞形......
采用纸层析、紫外分光光度法测定菜油、精炼油及抽油烟机回收油中苯并芘(3,4-benzapyrene,BaP)含量。结果显示:菜油中含有痕量BaP,精炼油中未检出BaP,批油烟机回收......
本文用苏乐康胶囊,剂量为39mg,每天1次灌胃,连续7天,抑制~(60)钴γ线全身照射0.5Gy和二乙基亚硝胺(DENA)皮下注射,剂量为0.1mg,每......
Optimizationofexperimentalconditionsinstudiesonmetabolismof4nitrobiphenylSongNing,XuXiaoaiResearchCenterforEcoEnvironment.........
二噁烷被国际癌症研究机构(IARC)定为2B类致癌物质,即对人类的潜在致癌性较小。二噁烷是生产AES的副产物,可以通过加强原料含水控制......
用黄曲霉毒素B1(AFB1)、苯并(a)芘(BaP)和2-乙基氨基芴(2-AAF)作为致癌物代表,研究限量饮食对雄性F344大鼠和B6C3F1小鼠代谢活化致癌物的影响。以几种致癌物主要的DNA加合物......
在过去的几年中,人们给予溴酸钾以极大关注,对其在面团及面包中作为氧化剂使用的安全问题提出质疑.本文就溴酸钾自1914年初次在美......
测定了不同牌号卷烟气焦油量与烟气中的3,4-苯并「a」芘、N-亚安等致癌物含量。结果发现,市售不同牌号卷烟烟气焦油量与致癌物含量各不相同......
Epigenetic alterations contribute significantly to the development and progression of gastric cancer,one of the leading ......
Carcinoma of the gallbladder (CaGB) is the fifth commonest gastrointestinal tract cancer and is endemic in several count......
目的 研究N-甲基亚硝基脲(MNU)诱发大白鼠膀胱肿瘤的发生、Q发展过程。方法 以MNU为诱癌剂,进行大白鼠膀胱灌注,对其诱发的膀胱肿瘤过程的不同......
恶性转化试验及在其基础上建立起来的相关试验体系是当前用于环境致癌因素检测的主要手段.本文以各种试验方法为核心,以试验中应用......
实验性颌面部恶性肿瘤动物模型是指:研究者通过使用物理、化学或生物的致癌因素(如诱癌剂、诱癌病毒、放射线等)作用于动物颌面部,使其......
用abinitio方法,在MP2/6—31G**水平下讨论了α-乙酰氧基-亚硝基吡咯烷(α—Acetoxy—NPYR)在各种条件下的解离反应机理,并对形成终致癌物......
目的:研究钱塘江水系中致癌物大致污染情况。方法:以淳安千岛湖作为对照点,以钱塘江水系中闻家堰、兰江和衢江段为调查区,对各个采样点......
背景与目的:抑癌基因启动子异常甲基化是肿瘤发生的重要机理之一,本研究探讨散发性乳腺癌癌变过程14-3-3σ基因启动子异常甲基化状......
在河流污染物中,致癌物、致突变物、致畸形物(简称“三致”物)毒性最强,对人体健康威胁最大,据检测,在黄河干流兰州段,包头段和郑州段等河......
p53基因是至今为止发现的与人类肿瘤相关性最高的基因.它不仅作为抑癌基因发挥作用,还参与细胞周期调控、DNA损伤与修复、基因转录......
水环境健康风险评价在参数确定、暴露评估与风险表征过程中存在着不确定性因素,利用随机模拟与三角模糊数耦合模型(SS-TFN模型)进行......
分析了饮用水中可能存在的有机和无机致癌物的种类、来源及致癌作用,并进一步探讨了水处理的物理化学技术和生物预处理技术在消除......
作者观察了1.2-二甲基肼(DMH)诱导大鼠大肠癌时,血清促胃液素(SG)的动态变化。表明:诱癌第8,23周时致癌组平均SG水平明显低于对照......
经腹腔、皮下及灌胃大剂量多次给予氧化铂,以诱发Wistar大鼠肿瘤,并对氧化铂的致癌作用进行了综合评估.结果发现:诱发的1例颌下腺......
妊娠BDⅨ大鼠经口给予氧化铂和硫化铂后1-3d,能使妊娠动物体重减轻,其后体重增加迟缓,胎盘以及胎鼠的重量降低分娩后在乳汁分泌不足或无汁。......
Development of a Raoult’s Law-Based Screening-Level Risk Assessment Methodology for Coal Tar and Its
A Raoult’s law-based screening-level assessment methodology was developed to calculate the carcinogenic and non-carcino......
Entropy Approach to the Study of Biological Activity of Chemical Compounds. The Other Side of Radiop
An attempt made to construct a model of relationship of the radioprotective and carcinogenic properties of biologically ......
Cr(VI) is a widespread environmental contaminant and a known human carcinogen. Biosorption is a very common method to re......
首次将AP-PCR应用于DNA多态性研究。研究了AP-PCR的反应程度,找到实现稳定扩增的适宜条件,并发现模板DNA浓度的变化在相当范围内不会改变扩增图谱;对肿瘤......
欧美于20世纪90年代开始系统研究环境内分泌干扰物(EDs),为此成立了专门的工作机构负责EDs研究的规划与协调工作。研究框架包括确认E......
香烟烟雾中含有大量致癌物质,吸烟者尿中可定量检测到多种烟草相关致癌物质及其代谢产物,如反-反式粘糠酸、苯巯基尿酸、4-甲基亚......
采用TBA(thiobatbrturic acid)法和ESR自旅标记技术,测定了无机致癌物重铬酸钾(Cr6+)对红细胞膜的蛋白巯基和磷脂的作用,结果表明,Cr......
Evaluation of Volatile Organic Compounds and Polyaromatic Hydrocarbons in Barker Reservoir in Housto
Analysis of volatile organic compounds (VOCs) and polyaromatic hydrocarbons (PAHs) in the Barker Reservoir in Houston, T......
The reaction mechanisms of carcinogenic methylating agent iodomethane (MeI) with keto and enol tautomers of thymine (K- ......
介绍了国内外学者当前较关注的微量元素之间及微量元素与致癌物的交互作用问题。...
r(VI) is a known human carcinogen. It is a wide spread environmental contaminant as it is extensively used in different ......
本文就手性污染物在生命过程中对映体的差异作了简要评述,分析了手性污染物对映体的毒性差异及机理,同时指出了手性污染物今后研究的......